hsa_circ_0005358 suppresses cervical cancer metastasis by interacting with PTBP1 protein to destabilize CDCP1 mRNA

• Main Authors: Yixuan Cen (Author), Tingjia Zhu (Author), Yanan Zhang (Author), Lu Zhao (Author), Jiawei Zhu (Author), Lingfang Wang (Author), Junfen Xu (Author), Tian Ding (Author), Xing Xie (Author), Xinyu Wang (Author), Weiguo Lu (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastasis is the main cause of cervical cancer lethality, but to date, no effective treatment has been developed to block metastasis. Circular RNAs (circRNAs) were recently found to be involved in cancer metastasis. In this study, we identified a downregulated circRNA derived from the host gene Gli...