Validation of Androgen Receptor loss as a risk factor for the development of brain metastases from ovarian cancers

• Main Authors: Gloria Mittica (Author), Margherita Goia (Author), Angela Gambino (Author), Giulia Scotto (Author), Mattia Fonte (Author), Rebecca Senetta (Author), Massimo Aglietta (Author), Fulvio Borella (Author), Anna Sapino (Author), Dionyssios Katsaros (Author), Furio Maggiorotto (Author), Eleonora Ghisoni (Author), Gaia Giannone (Author), Valentina Tuninetti (Author), Sofia Genta (Author), Chiara Eusebi (Author), Marina Momi (Author), Paola Cassoni (Author), Giorgio Valabrega (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Central nervous system (CNS) spreading from epithelial ovarian carcinoma (EOC) is an uncommon but increasing phenomenon. We previously reported in a small series of 11 patients a correlation between Androgen Receptor (AR) loss and localization to CNS. Aims of this study were: to...