Rapid and improved oral absorption of N-butylphthalide by sodium cholate-appended liposomes for efficient ischemic stroke therapy

• Main Authors: Ailing Zhang (Author), Jianbo Li (Author), Shuaishuai Wang (Author), Yaru Xu (Author), Qinglian Li (Author), Zhe Wu (Author), Chenxu Wang (Author), Haiyang Meng (Author), Jinjie Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a multi-target drug to treat ischemic stroke, N-butylphthalide (NBP) is extremely water-insoluble and exhibits limited oral bioavailability, impeding its wide oral application. Effective treatment of ischemic stroke by NBP requires timely and efficient drug exposure, necessitating the development...