Oral Treatment of Spontaneously Hypertensive Rats with Captopril-Surface Functionalized Furosemide-Loaded Multi-Wall Lipid-Core Nanocapsules

• Main Authors: Cecilia B. Michalowski (Author), Marcelo D. Arbo (Author), Louise Altknecht (Author), Andréia N. Anciuti (Author), Angélica S. G. Abreu (Author), Luciana M. R. Alencar (Author), Adriana R. Pohlmann (Author), Solange C. Garcia (Author), Sílvia S. Guterres (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Multi-wall lipid-core nanocapsule (MLNC) functionalized with captopril and nanoencapsulating furosemide within the core was developed as a liquid formulation for oral administration. The nanocapsules had mean particle size below 200 nm, showing unimodal and narrow size distributions with moderate di...