P53 and cancer-associated sialylated glycans are surrogate markers of cancerization of the bladder associated with Schistosoma haematobium infection.

• Main Authors: Júlio Santos (Author), Elisabete Fernandes (Author), José Alexandre Ferreira (Author), Luís Lima (Author), Ana Tavares (Author), Andreia Peixoto (Author), Beatriz Parreira (Author), José Manuel Correia da Costa (Author), Paul J Brindley (Author), Carlos Lopes (Author), Lúcio L Santos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly...