A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model.
To develop an oral formulation of amphotericin B (AmB) that is stable at the temperatures of WHO Climatic Zones 3 and 4 (30-43 °C) and to evaluate its efficacy in a murine model of visceral leishmaniasis (VL).The stability testing of four novel oral lipid AmB formulations composed of mono- and di-gl...
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Main Authors: | Ellen K Wasan (Author), Pavel Gershkovich (Author), Jinying Zhao (Author), Xiaohua Zhu (Author), Karl Werbovetz (Author), Richard R Tidwell (Author), John G Clement (Author), Sheila J Thornton (Author), Kishor M Wasan (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2010-12-01T00:00:00Z.
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