Mechanisms of antidepressant resistance

• Main Authors: Wissam eEl Hage (Author), Samuel eLeman (Author), Vincent eCamus (Author), Catherine eBelzung (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression is one of the most frequent and severe mental disorder. Since the discovery of antidepressant properties of the imipramine and then after of other tricyclic compounds, several classes of psychotropic drugs have shown be effective in treating major depressive disorder. However, there is a...