Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo.

Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected. Current drug treatment options are limited and lack efficacy against the worm, preventing an eradication programme. It is theref...

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Váldodahkkit: Frederick A Partridge (Dahkki), Emma A Murphy (Dahkki), Nicky J Willis (Dahkki), Carole J R Bataille (Dahkki), Ruth Forman (Dahkki), Narinder Heyer-Chauhan (Dahkki), Bruno Marinič (Dahkki), Daniel J C Sowood (Dahkki), Graham M Wynne (Dahkki), Kathryn J Else (Dahkki), Angela J Russell (Dahkki), David B Sattelle (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: Public Library of Science (PLoS), 2017-02-01T00:00:00Z.
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3rd Floor Main Library

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