Nano-Curcumin Prevents Cardiac Injury, Oxidative Stress and Inflammation, and Modulates TLR4/NF-κB and MAPK Signaling in Copper Sulfate-Intoxicated Rats

• Main Authors: Wedad S. Sarawi (Author), Ahlam M. Alhusaini (Author), Laila M. Fadda (Author), Hatun A. Alomar (Author), Awatif B. Albaker (Author), Amjad S. Aljrboa (Author), Areej M. Alotaibi (Author), Iman H. Hasan (Author), Ayman M. Mahmoud (Author)
• 格式: 圖書
• 出版: MDPI AG, 2021-09-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Copper (Cu) is essential for a plethora of biological processes; however, its high redox reactivity renders it potentially toxic. This study investigated the protective effect of curcumin (CUR) and nano-CUR (N-CUR) against Cu cardiotoxicity, emphasizing the role of oxidative stress, TLR4/NF-κB and m...