Prognostic Significance of Programmed Cell Death Ligand 1 (PD-L1), CD8+ Tumor-Infiltrating Lymphocytes and p53 in Non-Small Cell Lung Cancer: An Immunohistochemical Study

• Egile Nagusiak: Hayam E. RASHED (Egilea), Aziza E. ABDELRAHMAN (Egilea), Mohamed ABDELGAWAD (Egilea), Safa BALATA (Egilea), Mohamed El SHABRAWY (Egilea)
• Formatua: Liburua
• Argitaratua: Federation of Turkish Pathology Societies, 2017-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Programmed cell death ligand-1 interacts with the immune receptors on the surface of CD8+ tumor infiltrating lymphocytes and PD-1, thereby blocking its anti-tumor activity. Therapeutics suppression of this interaction will show a promise in the treatment of non-small cell lung cancer by r...