Improved Functionality of Integration-Deficient Lentiviral Vectors (IDLVs) by the Inclusion of IS₂ Protein Docks

• Main Authors: Marina Cortijo-Gutiérrez (Author), Sabina Sánchez-Hernández (Author), María Tristán-Manzano (Author), Noelia Maldonado-Pérez (Author), Lourdes Lopez-Onieva (Author), Pedro J. Real (Author), Concha Herrera (Author), Juan Antonio Marchal (Author), Francisco Martin (Author), Karim Benabdellah (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Integration-deficient lentiviral vectors (IDLVs) have recently generated increasing interest, not only as a tool for transient gene delivery, but also as a technique for detecting off-target cleavage in gene-editing methodologies which rely on customized endonucleases (ENs). Despite their broad pote...