89Zr-Radiolabeled Trastuzumab Imaging in Orthotopic and Metastatic Breast Tumors

• Автори: Albert J. Chang (Автор), Ravindra DeSilva (Автор), Sandeep Jain (Автор), Kimberley Lears (Автор), Suzanne Lapi (Автор), Buck Rogers (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2012-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The human epidermal growth factor receptor 2 (HER2/neu) is overexpressed in 20-30% of breast cancers and is associated with tumor growth, angiogenesis, and development of distant metastases. Trastuzumab, an anti-HER2 monoclonal antibody, is used for the treatment of HER2 positive breast cancer and c...