Frequency of HNF4A-P.I463V Variant in the Tunisian North-African Population and Its Relation with Diabetes Mellitus

• Main Authors: Abdelbasset Amara (Author), Ilhem Ben Charfeddine (Author), Houda Ghédir (Author), Ons Mamaï (Author), Saloua Jemni-Yacoub (Author), Larbi Chaieb (Author), Ali Saad (Author), Molka Chadli-Chaieb (Author), Moez Gribaa (Author)
• 格式: 圖書
• 出版: Tehran University of Medical Sciences, 2015-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Background: HNF4A-p.I463Vvariant, reported previously in two distinct families suspected of MODY-1, is assessed in this report to determine whether it is a mutation or a polymorphism (frequency >1%). Methods: 200 Tunisian healthy people were screened for the presence of HNF4A-p.I463V variant, usi...