Standardization of TP53 gene mutations analysis on oral squamous cell carcinoma from paraffin-embedded tissues

• Main Authors: José de Assis Silva Júnior (Author), Danielle Resende Camisasca (Author), Débora dos Santos Tavares (Author), Paulo Antônio Silvestre de Faria (Author), Fernando Luiz Dias (Author), Georgina Severo Ribeiro (Author), Lídia Maria da Fonte de Amorim (Author), Simone de Queiroz Chaves Lourenço (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction:The tumor protein p53 gene (TP53) is a constant target of investigation in cancer pathogenesis. Analysis by immunohistochemistry provides limited data about p53 in oral carcinogenesis, and TP53sequencing can contribute to this analysis. However, obtaining high-quality and contamination-...