Thalidomide Prevented and Ameliorated Pathogenesis of Crohn's Disease in Mice via Regulation of Inflammatory Response and Fibrosis

• Główni autorzy: Hongjin Chen (Autor), Haixia Xu (Autor), Lijiao Luo (Autor), Lichao Qiao (Autor), Yaohui Wang (Autor), Minmin Xu (Autor), Youran Li (Autor), Ping Zhu (Autor), Bolin Yang (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Crohn's disease (CD) is a chronic, relapsing form of inflammatory bowel disease, seriously threatening human health. Thalidomide has been used for the treatment of CD. However, the effects and the possible mechanisms of thalidomide on CD are still unclear. Herein, our study demonstrated that th...