Thalidomide Prevented and Ameliorated Pathogenesis of Crohn's Disease in Mice via Regulation of Inflammatory Response and Fibrosis

• Main Authors: Hongjin Chen (Author), Haixia Xu (Author), Lijiao Luo (Author), Lichao Qiao (Author), Yaohui Wang (Author), Minmin Xu (Author), Youran Li (Author), Ping Zhu (Author), Bolin Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Crohn's disease (CD) is a chronic, relapsing form of inflammatory bowel disease, seriously threatening human health. Thalidomide has been used for the treatment of CD. However, the effects and the possible mechanisms of thalidomide on CD are still unclear. Herein, our study demonstrated that th...