Process Model Approach to Predict Tablet Weight Variability for Direct Compression Formulations at Pilot and Production Scale

• Main Authors: Raghu V. G. Peddapatla (Author), Gerard Sheridan (Author), Conor Slevin (Author), Shrikant Swaminathan (Author), Ivan Browning (Author), Clare O'Reilly (Author), Zelalem A. Worku (Author), David Egan (Author), Stephen Sheehan (Author), Abina M. Crean (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Optimizing processing conditions to achieve a critical quality attribute (CQA) is an integral part of pharmaceutical quality by design (QbD). It identifies combinations of material and processing parameters ensuring that processing conditions achieve a targeted CQA. Optimum processing conditions are...