Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays
SARS-CoV-2 main protease (Mpro) is one of the most extensively exploited drug targets for COVID-19. Structurally disparate compounds have been reported as Mpro inhibitors, raising the question of their target specificity. To elucidate the target specificity and the cellular target engagement of the...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2022-04-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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