Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays

SARS-CoV-2 main protease (Mpro) is one of the most extensively exploited drug targets for COVID-19. Structurally disparate compounds have been reported as Mpro inhibitors, raising the question of their target specificity. To elucidate the target specificity and the cellular target engagement of the...

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Main Authors: Chunlong Ma (Author), Haozhou Tan (Author), Juliana Choza (Author), Yuyin Wang (Author), Jun Wang (Author)
Format: Book
Published: Elsevier, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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