The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

• Main Authors: Kumar Sudhesh (Author), O'Hare J Paul (Author), Bellary Srikanth (Author), Britten Abigail C (Author), Rees Simon D (Author), Barnett Anthony H (Author), Kelly M Ann (Author)
• Format: Book
• Published: BMC, 2009-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The <it>PCK1 </it>gene, encoding cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), has previously been implicated as a candidate gene for type 2 diabetes (T2D) susceptibility. Rodent models demonstrate that over-expr...