Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study

• Main Authors: Doaa I. Mohamed (Author), Doaa A. Abou-Bakr (Author), Samar F. Ezzat (Author), Hanaa F. Abd El-Kareem (Author), Hebatallah H. Abo Nahas (Author), Hosam A. Saad (Author), Amir E. Mehana (Author), Essa M. Saied (Author)
• Formato: Libro
• Publicado: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Testicular torsion (TT) is the most common urological emergency in children and young adults that can lead to infertility in many cases. The ischemia-reperfusion (IR) injury due to TT has been implicated in the pathogenesis of testicular damage. The main pathological mechanisms of contralateral inju...