Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment

• Main Authors: Narise K (Author), Okuda K (Author), Enomoto Y (Author), Hirayama T (Author), Nagasawa H (Author)
• Format: Book
• Published: Dove Medical Press, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Kosuke Narise, Kensuke Okuda, Yukihiro Enomoto, Tasuku Hirayama, Hideko Nagasawa Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Daigaku-nishi, Gifu, Japan Abstract: Adaptive cellular responses resulting from multiple microenvironmental stresses, such as hypoxia...