The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A.

• Main Authors: Viesta Beby Fadlitha (Author), Fuki Yamamoto (Author), Irfan Idris (Author), Haslindah Dahlan (Author), Naoya Sato (Author), Vienza Beby Aftitah (Author), Andini Febriyanda (Author), Takao Fujimura (Author), Hiroaki Takimoto (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leprosy is a chronic infection where the skin and peripheral nervous system is invaded by Mycobacterium leprae. The infection mechanism remains unknown in part because culture methods have not been established yet for M. leprae. Mce1A protein (442 aa) is coded by mce1A (1326 bp) of M. leprae. The Mc...