Association Study Between APOE and TNF- α Gene Variations and Sporadic Alzheimer's Disease in Iranian Population

• Autores principales: Niloufar Safavi Naini (Autor), Korush Kamali (Autor), Shideh Momeni (Autor), Masoud Karimloo (Autor), Mina Ohadi (Autor), Mahdi Manoochehri (Autor), Hamid Reza Khorram Khorshid (Autor)
• Formato: Libro
• Publicado: University of Social Welfare & Rehabilitation Sciences, 2012-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Objectives: Several studies indicate that amyloid ß (Aß) peptide deposits and neurofibrillary tangles have key roles in pathogenesis and progression of the late-onset Alzhimer’s disease. Likewise it has been shown that inflammatory reactions play a significant role as well. Inflammatory mediators su...