Association Study Between APOE and TNF- α Gene Variations and Sporadic Alzheimer's Disease in Iranian Population

• Main Authors: Niloufar Safavi Naini (Author), Korush Kamali (Author), Shideh Momeni (Author), Masoud Karimloo (Author), Mina Ohadi (Author), Mahdi Manoochehri (Author), Hamid Reza Khorram Khorshid (Author)
• Format: Book
• Published: University of Social Welfare & Rehabilitation Sciences, 2012-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Several studies indicate that amyloid ß (Aß) peptide deposits and neurofibrillary tangles have key roles in pathogenesis and progression of the late-onset Alzhimer’s disease. Likewise it has been shown that inflammatory reactions play a significant role as well. Inflammatory mediators su...