NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex

• Main Authors: Adrienne Bushau-Sprinkle (Author), Michelle T. Barati (Author), Kenneth B. Gagnon (Author), Syed Jalal Khundmiri (Author), Kathleen Kitterman (Author), Bradford G. Hill (Author), Amanda Sherwood (Author), Michael Merchant (Author), Shesh N. Rai (Author), Sudhir Srivastava (Author), Barbara Clark (Author), Leah Siskind (Author), Michael Brier (Author), Jessica Hata (Author), Eleanor Lederer (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Background: We previously showed Na/H exchange regulatory factor 1 (NHERF1) loss resulted in increased susceptibility to cisplatin nephrotoxicity. NHERF1-deficient cultured proximal tubule cells and proximal tubules from NHERF1 knockout (KO) mice exhibit altered mitochondrial protein expression...