The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.

• Main Authors: Colin M Fitzsimmons (Author), Frances M Jones (Author), Alex Stearn (Author), Iain W Chalmers (Author), Karl F Hoffmann (Author), Jakub Wawrzyniak (Author), Shona Wilson (Author), Narcis B Kabatereine (Author), David W Dunne (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. Located inside the tegument, the molecule belongs to a family of proteins from parasitic platyhelminths, the Tegument-Allergen-Like proteins (TALs). In addition to co...