Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells

• Main Authors: Yu Tai (Author), Lanjun Li (Author), Xuan Peng (Author), Junxue Zhu (Author), Xihai Mao (Author), Nan Qin (Author), Minghui Ma (Author), Rong Huo (Author), Yunlong Bai (Author), Deli Dong (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our previous studies found that mitochondrial uncouplers CCCP and niclosamide inhibited artery constriction and the mechanism involved AMPK activation in vascular smooth muscle cells. BAM15 is a novel type of mitochondrial uncoupler. The aim of the present study is to identify the vasoactivity of BA...