Metabolomic Analysis Reveals the Therapeutic Effects of MBT1805, a Novel Pan-Peroxisome Proliferator-Activated Receptor Agonist, on α-Naphthylisothiocyanate-Induced Cholestasis in Mice

• Päätekijät: Chang Wang (Tekijä), Fei Peng (Tekijä), Bohua Zhong (Tekijä), Ying Shi (Tekijä), Xiaomei Wang (Tekijä), Xueyuan Jin (Tekijä), Junqi Niu (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background and Aims: Therapeutic drugs that are used to treat cholestatic liver disease are limited; however, the results of clinical trials on primary biliary cholangitis treatment targeting peroxisome proliferator-activated receptors (PPARs) are encouraging. In this study, we aimed to identify the...