Comparing deep learning and immunohistochemistry in determining the site of origin for well-differentiated neuroendocrine tumors

• Main Authors: Jordan Redemann (Author), Fred A Schultz (Author), Cathy Martinez (Author), Michael Harrell (Author), Douglas P Clark (Author), David R Martin (Author), Joshua A Hanson (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Determining the site of origin for metastatic well-differentiated neuroendocrine tumors (WDNETs) is challenging, and immunohistochemical (IHC) profiles do not always lead to a definitive diagnosis. We sought to determine if a deep-learning convolutional neural network (CNN) could improve...