Synthesis and biological evaluation of novel 1,2,3-triazole hybrids of cabotegravir: identification of potent antitumor activity against lung cancer

• Main Authors: Yajie Guo (Author), Dan Sang (Author), Bin Guo (Author), Dan Wang (Author), Xinyue Xu (Author), Huili Wang (Author), Cuilan Hou (Author), Longfei Mao (Author), Fang Li (Author), Sanqiang Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In pursuit of discovering novel anticancer agents, we designed and synthesized a series of novel 1,2,3-triazole hybrids based on cabotegravir analogues. These compounds were subjected to initial biological evaluations to assess their anticancer activities against non-small-cell lung cancer (NSCLC)....