A Novel C Type CpG Oligodeoxynucleotide Exhibits Immunostimulatory Activity In Vitro and Enhances Antitumor Effect In Vivo

• Main Authors: Tete Li (Author), Jing Wu (Author), Shan Zhu (Author), Guoxia Zang (Author), Shuang Li (Author), Xinping Lv (Author), Wenjun Yue (Author), Yuan Qiao (Author), Jiuwei Cui (Author), Yan Shao (Author), Jun Zhang (Author), Yong-Jun Liu (Author), Jingtao Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundC type CpG oligodeoxynucleotides (CpG-C ODNs), possessing the features of both A type and B type CpG ODNs, exert a variety of immunostimulatory activities and have been demonstrated as an effective antitumor immunotherapy. Based on the structural characteristics, we designed 20 potential O...