Sera from patients with sepsis induce nitric oxide production in vascular smooth muscle cells

• Main Authors: Hiroshi Fujita (Author), Junji Tomiyama (Author), Hideki Kudo (Author), Ikuo Morita (Author), Sei-itsu Murota (Author)
• Format: Book
• Published: Hindawi Limited, 2000-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Nitric oxide (NO) is an important physiological mediator of vascular tone and is involved in pathophysiology of septic shock. Although plasma nitrite is a stable end product of NO oxidation derived from endogenous NO, the plasma nitrite level is also easily affected by the intake of vari...