Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma

• Main Authors: Zheqi Liu (Author), Zhen Zhang (Author), Yu Zhang (Author), Wenkai Zhou (Author), Xu Zhang (Author), Canbang Peng (Author), Tong Ji (Author), Xin Zou (Author), Zhiyuan Zhang (Author), Zhenhu Ren (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tumor progression is closely related to tumor tissue metabolism and reshaping of the microenvironment. Oral squamous cell carcinoma (OSCC), a representative hypoxic tumor, has a heterogeneous internal metabolic environment. To clarify the relationship between different metabolic regions and...