Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors

• Main Authors: Robert Pola (Author), Eliška Böhmová (Author), Marcela Filipová (Author), Michal Pechar (Author), Jan Pankrác (Author), David Větvička (Author), Tomáš Olejár (Author), Martina Kabešová (Author), Pavla Poučková (Author), Luděk Šefc (Author), Michal Zábrodský (Author), Olga Janoušková (Author), Jan Bouček (Author), Tomáš Etrych (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This report describes the design, synthesis and evaluation of tumor-targeted polymer probes to visualize epidermal growth factor receptor (EGFR)-positive malignant tumors for successful resection via fluorescence guided endoscopic surgery. Fluorescent polymer probes of various molecular weights enab...