C6/36 Aedes albopictus cells have a dysfunctional antiviral RNA interference response.

• Main Authors: Doug E Brackney (Author), Jaclyn C Scott (Author), Fumihiko Sagawa (Author), Jimmy E Woodward (Author), Neil A Miller (Author), Faye D Schilkey (Author), Joann Mudge (Author), Jeffrey Wilusz (Author), Ken E Olson (Author), Carol D Blair (Author), Gregory D Ebel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mosquitoes rely on RNA interference (RNAi) as their primary defense against viral infections. To this end, the combination of RNAi and invertebrate cell culture systems has become an invaluable tool in studying virus-vector interactions. Nevertheless, a recent study failed to detect an active RNAi r...