Lipid Peroxidation-Derived Aldehydes, 4-Hydroxynonenal and Malondialdehyde in Aging-Related Disorders

• Main Authors: Giuseppina Barrera (Author), Stefania Pizzimenti (Author), Martina Daga (Author), Chiara Dianzani (Author), Alessia Arcaro (Author), Giovanni Paolo Cetrangolo (Author), Giulio Giordano (Author), Marie Angele Cucci (Author), Maria Graf (Author), Fabrizio Gentile (Author)
• Format: Book
• Published: MDPI AG, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Among the various mechanisms involved in aging, it was proposed long ago that a prominent role is played by oxidative stress. A major way by which the latter can provoke structural damage to biological macromolecules, such as DNA, lipids, and proteins, is by fueling the peroxidation of membrane lipi...