Preparation and evaluation of a novel, live, attenuated influenza H1N1 vaccine strain produced by a modified classical reassortment method

• Main Authors: Yunfeng Long (Author), Lei Ma (Author), Ze Liu (Author), Shaohui Song (Author), Xingliang Geng (Author), Fan Yang (Author), Qi Guo (Author), Zhuofan Li (Author), Weidong Li (Author), Guoyang Liao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Live attenuated influenza vaccine (LAIV)-based Vero cells could provide a better choice to control and prevent influenza virus infections. This study used the human influenza virus A/Yunnan/1/2005Vca(H3N2) (YN/05Vca) as a donor strain. YN/05Vca has a double phenotype of cold adaption (ca) and Vero c...