Preparation and evaluation of a novel, live, attenuated influenza H1N1 vaccine strain produced by a modified classical reassortment method

• Autori principali: Yunfeng Long (Autore), Lei Ma (Autore), Ze Liu (Autore), Shaohui Song (Autore), Xingliang Geng (Autore), Fan Yang (Autore), Qi Guo (Autore), Zhuofan Li (Autore), Weidong Li (Autore), Guoyang Liao (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2018-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Live attenuated influenza vaccine (LAIV)-based Vero cells could provide a better choice to control and prevent influenza virus infections. This study used the human influenza virus A/Yunnan/1/2005Vca(H3N2) (YN/05Vca) as a donor strain. YN/05Vca has a double phenotype of cold adaption (ca) and Vero c...