Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine

• Main Authors: Ying Wang (Author), Jiaojiao Zhang (Author), Xinyu Cao (Author), Yaya Guan (Author), Shuang Shen (Author), Genshen Zhong (Author), Xiwen Xiong (Author), Yanhong Xu (Author), Xiaoying Zhang (Author), Hui Wang (Author), Jianping Ye (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IF1 (ATPIF1) is a nuclear DNA-encoded mitochondrial protein whose activity is inhibition of the F1Fo-ATP synthase to control ATP production. IF1 activity remains unknown in the regulation of GLP-1 activity. In this study, IF1 was examined in the diet-induced obese mice using the gene knockout (If1-K...