The epsilon toxin from Clostridium perfringens stimulates calcium‐activated chloride channels, generating extracellular vesicles in Xenopus oocytes

• Main Authors: Mercè Cases (Author), Jonatan Dorca‐Arévalo (Author), Marta Blanch (Author), Sergi Rodil (Author), Beatrice Terni (Author), Mireia Martín‐Satué (Author), Artur Llobet (Author), Juan Blasi (Author), Carles Solsona (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The epsilon toxin (Etx) from Clostridium perfringens has been identified as a potential trigger of multiple sclerosis, functioning as a pore‐forming toxin that selectively targets cells expressing the plasma membrane (PM) myelin and lymphocyte protein (MAL). Previously, we observed that Etx...