A Hybrid Peptide DEFB-TP5 Expressed in Methylotrophic Yeast Neutralizes LPS With Potent Anti-inflammatory Activities

• Main Authors: Baseer Ahmad (Author), Zhongxuan Li (Author), Quratulain Hanif (Author), Qingyong Hu (Author), Xubiao Wei (Author), Lulu Zhang (Author), Shahzad Akbar Khan (Author), Maierhaba Aihemaiti (Author), Huma Gulzar (Author), Muhammad Shahid (Author), Dayong Si (Author), Rijun Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DEFB-TP5 is a novel auspicious health-beneficial peptide derivative from two naturally occurring peptides, β-Defensin (DEFB) and thymopentin (TP5), and shows strong anti-inflammatory activity and binds to LPS without cytotoxicity and hemolytic effect. Furthermore, the application of DEFB-TP5 peptide...