1H NMR-Based Metabolomics Coupled With Molecular Docking Reveal the Anti-Diabetic Effects and Potential Active Components of Berberis vernae on Type 2 Diabetic Rats

• Main Authors: Qi Li (Author), Chengcheng Zhao (Author), Yunsen Zhang (Author), Huan Du (Author), Tong Xu (Author), Xinmei Xu (Author), Jing Zhang (Author), Tingting Kuang (Author), Xianrong Lai (Author), Gang Fan (Author), Yi Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dried stem bark of Berberis vernae C.K.Schneid., known as "Xiao-bo-pi" in Chinese, is a representative anti-diabetic herb in traditional Tibetan medical system. However, its anti-diabetic mechanisms and active components remain unclear. In this study, 1H NMR-based metabolomics, biochem...