Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10

• Main Authors: Jing Cheng (Author), Chunyang Li (Author), Yingfen Ying (Author), Jieqiang Lv (Author), Xianqin Qu (Author), Eileen McGowan (Author), Yiguang Lin (Author), Xueqiong Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Endometriosis affects endometrial receptivity, a key factor for successful embryo implantation. Metformin treatment is associated with alleviating the symptoms of endometriosis; however the mechanism of metformin action is unclear. Neoangiogenesis plays an important role in the developme...