Xuedan Sustained Release Pellets Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Targeting Gut Microbiota and MAPK Signaling Pathways

• Main Authors: Yingchun Zhang (Author), Dan Feng (Author), Yue Zeng (Author), Hanyu Zhang (Author), Xiaohong Du (Author), Yang Fu (Author), Xinhui Wang (Author), Dingyue Lian (Author), Ruikang Wang (Author), Hongyu Xiao (Author), Ning Wei (Author), Fuqiang Zhai (Author), Hanru Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cucurbitacins have a variety of bioactivities, such as anticancer, anti-inflammatory, antidepressant-like, and antiviral effects, but their pharmacological effect in ulcerative colitis (UC) has not been reported until now. Thus, this study aims to investigate the preventive effects of Xuedan sustain...