Increased interleukin-17 in peripheral blood and cerebrospinal fluid of neurosyphilis patients.

• Main Authors: Cuini Wang (Author), Lin Zhu (Author), Zixiao Gao (Author), Zhifang Guan (Author), Haikong Lu (Author), Mei Shi (Author), Ying Gao (Author), Huanbin Xu (Author), X Frank Yang (Author), Pingyu Zhou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Treponema pallidum infection evokes vigorous immune responses, resulting in tissue damage. Several studies have demonstrated that IL-17 may be involved in the pathogenesis of syphilis. However, the role of Th17 response in neurosyphilis remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: In...