Overcoming barriers: a review on innovations in drug delivery to the middle and inner ear

• Egile Nagusiak: Derek S. Delaney (Egilea), Lawrence J. Liew (Egilea), Joey Lye (Egilea), Marcus D. Atlas (Egilea), Elaine Y. M. Wong (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Despite significant advances in the development of therapeutics for hearing loss, drug delivery to the middle and inner ear remains a challenge. As conventional oral or intravascular administration are ineffective due to poor bioavailability and impermeability of the blood-labyrinth-barrier, localiz...