Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer's Disease

• Main Authors: Yuan Sun (Author), Xue Song Yin (Author), Hong Guo (Author), Rong Kun Han (Author), Rui Dong He (Author), Li Jun Chi (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory mediators are closely associated with the pathogenesis of neurodegenerative changes in Alzheimer's disease (AD) and mild cognitive impairment (MCI). Osteopontin (OPN) is a proinflammatory cytokine that has been shown to play an important role in various neuroinflammatory diseases....