New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties

• Main Authors: Panpan Ma (Author), Balthazar Toussaint (Author), Enrica Angela Roberti (Author), Noémie Scornet (Author), Axel Santos Silva (Author), Luis Castillo Henríquez (Author), Monique Cadasse (Author), Philippe Négrier (Author), Stéphane Massip (Author), Hanh Dufat (Author), Karim Hammad (Author), Cecilia Baraldi (Author), Maria Cristina Gamberini (Author), Cyrille Richard (Author), Stéphane Veesler (Author), Philippe Espeau (Author), Tu Lee (Author), Yohann Corvis (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study describes the preparation, characterization, and influence of the enantiopure vs. racemic coformer on the physico-chemical properties of a pharmaceutical cocrystal. For that purpose, two new 1:1 cocrystals, namely lidocaine:<span style="font-variant: small-caps;">dl</sp...