Continuous melt granulation to develop high drug loaded sustained release tablet of Metformin HCl

The present work explores the application of melt granulation technology to develop a high drug loaded sustained release matrix tablet of Metformin HCl using hydroxypropylcellulose (HPC) as a hydrophilic binder and stearic acid as an extrusion aid for producing cohesive granules. This novel approach...

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Bibliographic Details
Main Authors: Pradnya Vaingankar (Author), Purnima Amin (Author)
Format: Book
Published: Elsevier, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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