Continuous melt granulation to develop high drug loaded sustained release tablet of Metformin HCl
The present work explores the application of melt granulation technology to develop a high drug loaded sustained release matrix tablet of Metformin HCl using hydroxypropylcellulose (HPC) as a hydrophilic binder and stearic acid as an extrusion aid for producing cohesive granules. This novel approach...
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| Autori principali: | , |
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| Natura: | Libro |
| Pubblicazione: |
Elsevier,
2017-01-01T00:00:00Z.
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| Collocazione: |
A1234.567 |
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