Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice

Abstract Background Sepsis is characterized as an insulin resistant state. However, the effects of sepsis on insulin's signal transduction pathway are unknown. The molecular activity driving insulin signaling is controlled by tyrosine phosphorylation of the insulin receptor β-subunit (IRβ) and...

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Main Authors: Deepa Mathew (Author), Julia Barillas-Cerritos (Author), Ana Nedeljkovic-Kurepa (Author), Mabel Abraham (Author), Matthew D. Taylor (Author), Clifford S. Deutschman (Author)
Format: Book
Published: BMC, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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