Computer-assisted discovery of safe and effective DprE1/ aaRSs Inhibitors against TB utilizing Drug Repurposing approach
Background: The emergence of various drug-resistant strains of Mycobacterium tuberculosis compelled medicinal chemists to expedite the discovery of novel, safer alternatives to present regimens. Decaprenylphosphoryl-β-d-ribose 2'-epimerase (DprE1), an essential component of arabinogalactan bios...
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Elsevier,
2023-04-01T00:00:00Z.
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